Galectin-3 in a Sample of Hospitalized Class IV NYHA Heart Failure Patients
نویسندگان
چکیده
منابع مشابه
CRT-D therapy in heart failure: how much do NYHA class IV patients benefit?
Patients with advanced heart failure (HF) have high mortality rates, to a relatively greater extent in those with New York Heart Association (NYHA) functional class IV versus III, justifying consideration of cardiac transplantation in this high-risk population.1,2 For many of these patients, gains in pharmacologic therapy have helped significantly in delaying progression to transplantation requ...
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Galectins are a family of soluble β-galactoside-binding lectins that have important role in inflammation, immunity, and cancer. Galectin-3 as a part of this lectin family plays a very important role in development of heart failure. According to recent papers, galectin-3 plasma level correlates with heart failure outcome, primarily with rehospitalisation and death from heart failure. This paper ...
متن کاملGalectin-3 in Ambulatory Patients With Heart Failure
Background—Galectin-3 is a soluble ß-galactoside–binding lectin released by activated cardiac macrophages. Elevated levels of galectin-3 have been found to be associated with adverse outcomes in patients with heart failure. We evaluated the association between galectin-3 and long-term clinical outcomes in ambulatory heart failure patients enrolled in the HF-ACTION study. Methods and Results—HF-...
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BACKGROUND Heart failure (HF), a debilitating disease in a growing number of adults, exerts structural and neurohormonal changes in both cardiac and skeletal muscles. However, these alterations and their affected molecular pathways remain uncharacterized. Disease progression is known to transform skeletal muscle fiber composition by unknown mechanisms. In addition, perturbation of specific horm...
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During a period of four years between June, IS, 1988 to June, IS, 1992 one hundred and fourteen patients with congestive heart failure (CHF) were admitted to the pediatric department of Taleghani General Hospital. During the above period, 192 patients with heart disease were hospitalized at this department and CHF was the cause of admission in 59.4% of them. Congenital heart disease (CHO) w...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2013
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2013.08.338